FAAH2

Across TCGA pan-cancer cohorts, FAAH2 Mutation is linked to patient survival in 10 of 34 cancer types, making it a survival-associated FAAH2 data layer compared with 22 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher FAAH2 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FAAH2 expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

ESCA, STAD, and CESC are the cancer types where FAAH2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Median	II,III,IV	0.102	0.703	<.001	36	view →
STAD	OS	Median	II,III,IV	0.196	0.660	.015	21	view →
CESC	OS	Median	All	0.261	0.798	.006	12	view →
DLBC	OS	Median	II,III,IV	0.118	0.802	.025	12	view →
COAD	OS	Median	III,IV	0.157	0.791	.001	6	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
LUAD	DFS	Median	IV	0.342	0.893	<.001	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
LUSC	DFS	Median	II,III,IV	0.139	0.663	.027	3	view →
SKCM	DFS	Median	III,IV	1.000	0.265	.044	1	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

FAAH2–ESCA (OS)

Open the ESCA breakdown →