Across TCGA patient cohorts, F8 protein abundance is significantly associated with the RNA expression of many other genes, with 4,493 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible F8-associated genes across cancer lineages are PRG4, BRCA1, and TUBG1. Each is linked with F8 in more than 2 cancer types. Because this analysis shows association rather than direction, both F8-to-partner and partner-to-F8 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (F8→partner) and Y-score (partner→F8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PRG4 →	+0.465	+0.267	<.001	<.001	3	3
GBM	BRCA1 →	-1.257	-0.682	.001	<.001	3	3
GBM	TUBG1 →	-0.684	-0.694	<.001	.001	3	3
LSCC	MMRN1 →	+1.205	+0.535	<.001	<.001	3	3
LSCC	RDM1 →	-0.569	-0.365	.003	.004	3	3
GBM	CASS4 →	+0.961	+0.668	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,493 associations by consensus.

Exploration

F8 survival (RNA) · tumor vs normal (RNA) · all F8 data types