F7

Across TCGA pan-cancer cohorts, F7 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated F7 data layer compared with 23 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher F7 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated F7 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and HNSC show a favorable association.

LUAD, PDAC, and CCRCC are the cancer types where F7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	III,IV	0.240	0.741	.002	32	view →
PDAC	OS	Tertile	II,III,IV	0.357	0.951	.006	21	view →
CCRCC	DFS	Tertile	III,IV	0.737	0.242	.001	16	view →
HNSC	DFS	Median	All	0.947	0.331	.014	9	view →
GBM	OS	Quartile	All	0.949	0.645	.009	7	view →
UCEC	DFS	Tertile	II,III,IV	0.846	0.273	.028	4	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

F7–LUAD (OS)

Open the LUAD breakdown →