F7

Across TCGA cell cohorts, F7 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible F7-associated genes across cancer lineages are C9orf92, KCNK18, and PRAMEF9. Each is linked with F7 in more than 1 cancer types. Because this analysis shows association rather than direction, both F7-to-partner and partner-to-F7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C9orf92 grouped by F7-low versus F7-high in UPPER_AERODIGESTIVE_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (F7→partner) and Y-score (partner→F7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	C9orf92 →	+0.456	+4.736	<.001	.009	3	2
LUNG_NSCLC_LUAD	KCNK18 →	+0.019	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	PRAMEF9 →	+0.012	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	DEFB133 →	+0.194	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	SPATA31D1 →	+0.006	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	KRTAP19-3 →	+0.132	+5.228	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

C9orf92 by F7 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →