Across TCGA cell cohorts, F5 mutation is significantly associated with the RNA expression of many other genes, with 811 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible F5-associated genes across cancer lineages are OR52N1, SCGB1C2, and C3orf80. Each is linked with F5 in more than 1 cancer types. Because this analysis shows association rather than direction, both F5-to-partner and partner-to-F5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (F5→partner) and Y-score (partner→F5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR52N1 →	+0.036	+3.058	<.001	.002	3	2
BLOOD_Lymphoma	SCGB1C2 →	+0.043	+3.662	<.001	.009	3	2
SKIN	C3orf80 →	+0.633	+3.364	<.001	.002	3	2
LARGE_INTESTINE	NPM3 →	+0.587	+2.628	.005	.002	3	2
LARGE_INTESTINE	S100PBP →	+0.698	+2.628	.001	.002	3	2
LARGE_INTESTINE	KDSR →	+0.778	+2.628	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 811 associations by consensus.

Exploration

F5 survival (RNA) · tumor vs normal (RNA) · all F5 data types