F3

Across TCGA patient cohorts, F3 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,748 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible F3-associated proteins across cancer lineages are HCFC1, BPTF, and DHX9. Each is linked with F3 in more than 5 cancer types. Because this analysis shows association rather than direction, both F3-to-partner and partner-to-F3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, F3 versus HCFC1 in GBM, with a Pearson correlation of -0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (F3→partner) and Y-score (partner→F3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HCFC1 →	-0.279	-1.154	<.001	<.001	3	6
BRCA	BPTF →	-0.287	-1.083	<.001	<.001	3	5
OV	DHX9 →	-0.287	-1.085	<.001	.004	3	5
HNSC	LAMA3 →	+0.757	+1.151	<.001	<.001	3	5
PDAC	LAMB3 →	+0.830	+0.803	<.001	<.001	3	5
LUAD	S100P →	+1.824	+1.143	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,748 associations by consensus.

F3 vs HCFC1 — GBM

Explore this scatter interactively →