F3

Across TCGA patient cohorts, F3 protein abundance is significantly associated with the RNA expression of many other genes, with 10,295 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible F3-associated genes across cancer lineages are TSPAN1, ETNK2, and CACNA2D1. Each is linked with F3 in more than 4 cancer types. Because this analysis shows association rather than direction, both F3-to-partner and partner-to-F3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, F3 versus TSPAN1 in LSCC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (F3→partner) and Y-score (partner→F3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TSPAN1 →	+1.525	+0.897	<.001	<.001	3	5
HNSC	ETNK2 →	-1.001	-0.873	<.001	<.001	3	4
HNSC	CACNA2D1 →	-1.153	-0.803	<.001	.001	3	4
LUAD	TFF1 →	+2.484	+0.724	.006	.002	3	4
LSCC	JAKMIP2 →	-1.095	-0.923	<.001	<.001	3	4
LUAD	MYOZ1 →	-1.136	-0.786	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,295 associations by consensus.

F3 vs TSPAN1 — LSCC

Explore this scatter interactively →