F3

Across TCGA patient cohorts, F3 mutation is significantly associated with the RNA expression of many other genes, with 318 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible F3-associated genes across cancer lineages are RN7SL447P, SLC2A8, and MIR378E. Each is linked with F3 in more than 1 cancer types. Because this analysis shows association rather than direction, both F3-to-partner and partner-to-F3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL447P grouped by F3-low versus F3-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (F3→partner) and Y-score (partner→F3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL447P →	+0.163	+5.201	<.001	.007	3	2
UCEC	SLC2A8 →	+0.664	+3.491	<.001	.002	3	2
UCEC	MIR378E →	+0.349	+3.716	<.001	.002	3	2
COAD	SNORD116-17 →	+1.112	+5.790	<.001	.003	3	2
BLCA	RNU6ATAC19P →	+0.328	+7.640	<.001	.009	3	1
BLCA	OR3B1P →	+0.049	+7.640	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 318 associations by consensus.

RN7SL447P by F3 expression — CESC

Explore this box plot interactively →