F3

Across TCGA cell cohorts, F3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,759 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible F3-associated GO terms across cancer lineages are Blood coagulation, extrinsic pathway, Activation of blood coagulation via clotting cascade, and Positive regulation of chemotaxis. Each is linked with F3 in more than 17 cancer types. Because this analysis shows association rather than direction, both F3-to-partner and partner-to-F3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Blood coagulation, extrinsic pathway grouped by F3-low versus F3-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (F3→partner) and Y-score (partner→F3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Blood coagulation, extrinsic pathway →	+1.785	+4.512	<.001	<.001	3	18
BREAST	Activation of blood coagulation via clotting cascade →	+0.444	+2.819	<.001	<.001	3	16
LUNG_NSCLC_LUSC	Positive regulation of chemotaxis →	+0.126	+4.918	.001	<.001	3	15
BONE	Wound healing →	+0.116	+2.390	<.001	.001	3	15
BONE	Integrin-mediated signaling pathway →	+0.171	+1.933	.001	<.001	3	15
LUNG_NSCLC_LUSC	Urokinase plasminogen activator signaling pathway →	+1.133	+3.597	.004	.002	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,759 associations by consensus.

Blood coagulation, extrinsic pathway by F3 expression — KIDNEY

Explore this box plot interactively →