F11

Across TCGA pan-cancer cohorts, F11 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated F11 data layer compared with 21 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher F11 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated F11 expression acts as an unfavorable survival marker, although some lineages such as GBM show a favorable association.

LUAD, COAD, and LSCC are the cancer types where F11 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	II,III,IV	0.367	0.824	.001	27	view →
COAD	DFS	Median	II,III,IV	0.847	1.000	.034	18	view →
LSCC	DFS	Median	II,III,IV	0.823	1.000	.002	16	view →
CCRCC	DFS	Median	II,III,IV	0.235	0.887	.005	7	view →
HNSC	OS	Tertile	III,IV	0.564	0.732	.032	3	view →
GBM	DFS	Median	All	0.421	0.225	.049	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

F11–LUAD (OS)

Open the LUAD breakdown →