F11

Across TCGA patient cohorts, F11 protein abundance is significantly associated with the RNA expression of many other genes, with 15,216 significant associations in total. GBM shows the largest number of these associations.

The most reproducible F11-associated genes across cancer lineages are IL6, SFRP2, and COLEC12. Each is linked with F11 in more than 7 cancer types. Because this analysis shows association rather than direction, both F11-to-partner and partner-to-F11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, F11 versus IL6 in LSCC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (F11→partner) and Y-score (partner→F11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	IL6 →	+1.587	+0.491	<.001	<.001	3	8
COAD	SFRP2 →	+2.205	+0.561	.005	.004	3	8
GBM	COLEC12 →	+1.207	+0.541	<.001	<.001	3	8
LUAD	ADAMTS4 →	+1.008	+0.297	<.001	<.001	3	8
BRCA	PLPP7 →	+0.527	+0.609	<.001	<.001	3	8
GBM	COL6A3 →	+1.557	+0.558	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,216 associations by consensus.

F11 vs IL6 — LSCC

Explore this scatter interactively →