EZR

Across TCGA patient cohorts, EZR RNA expression is significantly associated with the protein abundance of many other proteins, with 9,023 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible EZR-associated proteins across cancer lineages are EZR_S535, AFDN, and KRT8. Each is linked with EZR in more than 7 cancer types. Because this analysis shows association rather than direction, both EZR-to-partner and partner-to-EZR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EZR versus EZR_S535 in LUAD, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EZR→partner) and Y-score (partner→EZR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	EZR_S535 →	+0.556	+0.720	<.001	<.001	3	8
BRCA	AFDN →	+0.344	+0.640	.009	.001	3	5
BRCA	KRT8 →	+0.628	+0.732	.005	<.001	3	5
BRCA	ITPRID2 →	+0.506	+0.553	.004	.001	3	5
CCRCC	EZR_S413 →	+0.664	+0.798	<.001	<.001	3	5
CCRCC	CEP43 →	+0.400	+0.756	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,023 associations by consensus.

EZR vs EZR_S535 — LUAD

Explore this scatter interactively →