EZR

Across TCGA patient cohorts, EZR protein abundance is significantly associated with the RNA expression of many other genes, with 11,406 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible EZR-associated genes across cancer lineages are EZR-AS1, SFT2D1, and DYNLT1. Each is linked with EZR in more than 6 cancer types. Because this analysis shows association rather than direction, both EZR-to-partner and partner-to-EZR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EZR versus EZR-AS1 in CCRCC, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EZR→partner) and Y-score (partner→EZR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	EZR-AS1 →	+0.919	+0.524	<.001	<.001	3	7
OV	SFT2D1 →	+0.484	+0.493	.004	<.001	3	6
UCEC	DYNLT1 →	+0.478	+0.373	.006	.001	3	6
BRCA	C6orf99 →	+0.650	+0.399	<.001	<.001	3	6
UCEC	AGR2 →	+2.407	+0.489	<.001	<.001	3	5
OV	MRPL18 →	+0.646	+0.487	<.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,406 associations by consensus.

EZR vs EZR-AS1 — CCRCC

Explore this scatter interactively →