EZR

Across TCGA cell cohorts, EZR RNA expression is significantly associated with the go_rna of many other GO terms, with 4,482 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible EZR-associated GO terms across cancer lineages are Intestinal D-glucose absorption, Positive regulation of receptor localization to synapse, and Intestinal hexose absorption. Each is linked with EZR in more than 14 cancer types. Because this analysis shows association rather than direction, both EZR-to-partner and partner-to-EZR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intestinal D-glucose absorption grouped by EZR-low versus EZR-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EZR→partner) and Y-score (partner→EZR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Intestinal D-glucose absorption →	+0.258	+1.106	<.001	<.001	3	15
PANCREAS	Positive regulation of receptor localization to synapse →	+0.143	+1.435	.004	<.001	3	14
BONE	Intestinal hexose absorption →	+0.320	+1.274	<.001	<.001	3	14
PANCREAS	Positive regulation of multicellular organism growth →	+0.157	+0.857	<.001	.002	3	11
LUNG_NSCLC_LUSC	Protein localization to plasma membrane →	+0.074	+1.078	<.001	.009	3	10
LUNG_NSCLC_LUSC	Blood coagulation, intrinsic pathway →	+0.462	+1.990	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,482 associations by consensus.

Intestinal D-glucose absorption by EZR expression — SKIN

Explore this box plot interactively →