EZH1

Across TCGA patient cohorts, EZH1 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,032 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EZH1-associated proteins across cancer lineages are PHC3, RPL5, and SAP30L. Each is linked with EZH1 in more than 6 cancer types. Because this analysis shows association rather than direction, both EZH1-to-partner and partner-to-EZH1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EZH1 versus PHC3 in BRCA, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EZH1→partner) and Y-score (partner→EZH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PHC3 →	+0.431	+0.712	<.001	<.001	3	7
LUAD	RPL5 →	-0.235	-0.335	<.001	<.001	3	7
PDAC	SAP30L →	+0.418	+0.356	<.001	<.001	3	7
LSCC	FAM98B →	+0.326	+0.477	<.001	<.001	3	7
HNSC	SMC1A →	+0.206	+0.408	<.001	<.001	3	6
LSCC	NFYC →	+0.294	+0.472	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,032 associations by consensus.

EZH1 vs PHC3 — BRCA

Explore this scatter interactively →