EZH1

Across TCGA patient cohorts, EZH1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,891 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EZH1-associated genes across cancer lineages are KIF20A, PSAT1, and PLK1. Each is linked with EZH1 in more than 3 cancer types. Because this analysis shows association rather than direction, both EZH1-to-partner and partner-to-EZH1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EZH1 versus KIF20A in BRCA, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EZH1→partner) and Y-score (partner→EZH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	KIF20A →	-1.154	-0.466	<.001	<.001	3	4
BRCA	PSAT1 →	-1.799	-0.311	<.001	.002	3	4
BRCA	PLK1 →	-0.899	-0.385	.001	.001	3	4
UCEC	ARHGEF6 →	+0.777	+0.310	<.001	<.001	3	4
LUAD	RAB37 →	+0.543	+0.194	<.001	.001	3	4
BRCA	FANCA →	-0.682	-0.341	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,891 associations by consensus.

EZH1 vs KIF20A — BRCA

Explore this scatter interactively →