EYA4

Across TCGA patient cohorts, EYA4 protein abundance is significantly associated with the RNA expression of many other genes, with 884 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EYA4-associated genes across cancer lineages are KIAA0753, NR2F6, and USE1. Each is linked with EYA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both EYA4-to-partner and partner-to-EYA4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EYA4 versus KIAA0753 in LUAD, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EYA4→partner) and Y-score (partner→EYA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	KIAA0753 →	+0.560	+0.865	.006	.004	3	2
OV	NR2F6 →	+1.310	+1.382	<.001	<.001	3	2
OV	USE1 →	+1.066	+1.497	<.001	<.001	3	2
LUAD	SRRD →	+0.521	+1.195	.007	.004	3	1
LUAD	SAMM50 →	+0.436	+0.759	.003	.003	3	1
LUAD	PABPN1 →	-0.531	-0.971	.007	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 884 associations by consensus.

EYA4 vs KIAA0753 — LUAD

Explore this scatter interactively →