EYA4

Across TCGA cell cohorts, EYA4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,699 significant associations in total. CNS shows the largest number of these associations.

The most reproducible EYA4-associated GO terms across cancer lineages are DNA-templated transcription initiation, RNA localization, and Nuclear-transcribed mRNA catabolic process. Each is linked with EYA4 in more than 9 cancer types. Because this analysis shows association rather than direction, both EYA4-to-partner and partner-to-EYA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription initiation grouped by EYA4-low versus EYA4-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EYA4→partner) and Y-score (partner→EYA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	DNA-templated transcription initiation →	+0.069	+1.294	.005	.003	3	9
BREAST	RNA localization →	+0.065	+1.129	.002	.002	2	10
LIVER	Nuclear-transcribed mRNA catabolic process →	+0.044	+1.848	.004	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Transcription initiation at RNA polymerase II promoter →	+0.068	+1.294	.002	.002	2	9
OESOPHAGUS	Transcription preinitiation complex assembly →	+0.076	+0.980	.001	.006	2	9
LIVER	Establishment of protein localization to organelle →	+0.051	+2.688	.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,699 associations by consensus.

DNA-templated transcription initiation by EYA4 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →