EYA2

Across TCGA pan-cancer cohorts, EYA2 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated EYA2 data layer compared with 24 for mass-spec protein and 9 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher EYA2 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated EYA2 expression acts as an unfavorable survival marker, although some lineages such as UCEC and GBM show a favorable association.

UCEC, GBM, and LSCC are the cancer types where EYA2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	III,IV	1.000	0.315	.022	8	view →
GBM	OS	Median	All	0.663	0.296	.001	7	view →
LSCC	DFS	Median	All	0.306	1.000	.004	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

EYA2–UCEC (OS)

Open the UCEC breakdown →