EYA1

Across TCGA patient cohorts, EYA1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,416 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EYA1-associated genes across cancer lineages are USP34, ZMYM2, and ATXN1. Each is linked with EYA1 in more than 2 cancer types. Because this analysis shows association rather than direction, both EYA1-to-partner and partner-to-EYA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EYA1 versus USP34 in GBM, with a Pearson correlation of -0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EYA1→partner) and Y-score (partner→EYA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	USP34 →	-0.746	-0.653	<.001	.006	3	3
GBM	ZMYM2 →	-0.720	-0.496	.003	.001	3	3
GBM	ATXN1 →	-0.691	-0.706	<.001	.007	3	3
GBM	ATM →	-0.693	-0.686	<.001	.005	3	3
GBM	SMARCA5 →	-0.601	-0.744	.002	.002	3	3
GBM	HDGFL3 →	-0.910	-0.885	.002	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,416 associations by consensus.

EYA1 vs USP34 — GBM

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