EYA1

Across TCGA cell cohorts, EYA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,467 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible EYA1-associated GO terms across cancer lineages are Potassium ion transmembrane transport, Keratinocyte activation, and Endoplasmic reticulum to Golgi vesicle-mediated transport. Each is linked with EYA1 in more than 5 cancer types. Because this analysis shows association rather than direction, both EYA1-to-partner and partner-to-EYA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Potassium ion transmembrane transport grouped by EYA1-low versus EYA1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EYA1→partner) and Y-score (partner→EYA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Potassium ion transmembrane transport →	-0.042	-0.342	<.001	.007	3	6
LUNG_NSCLC_LUAD	Keratinocyte activation →	+0.680	+0.629	.002	<.001	3	6
LARGE_INTESTINE	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.036	+0.207	.006	.004	3	6
OVARY	Action potential →	-0.053	-0.339	.002	.007	3	5
OVARY	Positive regulation of lung ciliated cell differentiation →	+1.137	+0.604	<.001	.001	3	5
SKIN	Regulation of non-motile cilium assembly →	+0.065	+1.471	.006	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,467 associations by consensus.

Potassium ion transmembrane transport by EYA1 expression — OVARY

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