EXTL2

Across TCGA patient cohorts, EXTL2 RNA expression is significantly associated with the RNA expression of many other genes, with 20,470 significant associations in total. ACC shows the largest number of these associations.

The most reproducible EXTL2-associated genes across cancer lineages are SLC30A7, FAM161A, and TRMT61B. Each is linked with EXTL2 in more than 33 cancer types. Because this analysis shows association rather than direction, both EXTL2-to-partner and partner-to-EXTL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EXTL2 versus SLC30A7 in UVM, with a Pearson correlation of 0.93.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EXTL2→partner) and Y-score (partner→EXTL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	SLC30A7 →	+1.502	+1.517	<.001	<.001	3	34
UVM	FAM161A →	+1.274	+1.330	<.001	<.001	3	34
UVM	TRMT61B →	+1.471	+1.382	<.001	<.001	3	34
UVM	CEP83 →	+1.411	+1.356	<.001	<.001	3	34
UVM	UBXN2A →	+1.466	+1.413	<.001	<.001	3	34
UVM	CEP290 →	+1.306	+1.348	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,470 associations by consensus.

EXTL2 vs SLC30A7 — UVM

Explore this scatter interactively →