EXTL2

Across TCGA cell cohorts, EXTL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,695 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EXTL2-associated GO terms across cancer lineages are UDP-N-acetylgalactosamine metabolic process, Protein localization to cilium, and Protein localization to ciliary membrane. Each is linked with EXTL2 in more than 19 cancer types. Because this analysis shows association rather than direction, both EXTL2-to-partner and partner-to-EXTL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UDP-N-acetylgalactosamine metabolic process grouped by EXTL2-low versus EXTL2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EXTL2→partner) and Y-score (partner→EXTL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	UDP-N-acetylgalactosamine metabolic process →	+1.300	+1.327	<.001	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	Protein localization to cilium →	+0.070	+1.437	<.001	<.001	3	15
STOMACH	Protein localization to ciliary membrane →	+0.106	+0.835	.003	<.001	3	12
STOMACH	Zinc ion import into Golgi lumen →	+0.103	+0.920	.008	.003	2	13
UPPER_AERODIGESTIVE_TRACT	Regulation of telomere maintenance →	+0.055	+1.027	.003	.006	3	12
BREAST	Mitotic spindle assembly →	+0.107	+1.081	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,695 associations by consensus.

UDP-N-acetylgalactosamine metabolic process by EXTL2 expression — OESOPHAGUS

Explore this box plot interactively →