EXTL2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, EXTL2 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible EXTL2-associated genes across cancer lineages are RD3. Each is linked with EXTL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both EXTL2-to-partner and partner-to-EXTL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RD3 grouped by EXTL2-low versus EXTL2-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EXTL2→partner) and Y-score (partner→EXTL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHRD3 →+0.149+4.700<.001.00721
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

RD3 by EXTL2 expression — STOMACH

Box plot of RD3 in EXTL2-low vs EXTL2-high samples in STOMACH.

Explore this box plot interactively →

Exploration