EXT2

Across TCGA patient cohorts, EXT2 RNA expression is significantly associated with the RNA expression of many other genes, with 20,037 significant associations in total. ACC shows the largest number of these associations.

The most reproducible EXT2-associated genes across cancer lineages are SPTY2D1, GMFB, and MBTPS2. Each is linked with EXT2 in more than 33 cancer types. Because this analysis shows association rather than direction, both EXT2-to-partner and partner-to-EXT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EXT2 versus SPTY2D1 in KICH, with a Pearson correlation of 0.80.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EXT2→partner) and Y-score (partner→EXT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KICH	SPTY2D1 →	+1.406	+0.755	<.001	<.001	3	34
UVM	GMFB →	+1.444	+0.751	<.001	<.001	3	34
TGCT	MBTPS2 →	+1.054	+1.091	<.001	<.001	3	34
THYM	ITGB1 →	+2.105	+0.844	<.001	<.001	3	34
KICH	ZNF639 →	+0.850	+0.779	<.001	<.001	3	34
KICH	AZI2 →	+1.150	+0.755	<.001	<.001	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,037 associations by consensus.

EXT2 vs SPTY2D1 — KICH

Explore this scatter interactively →