EXT2

Across TCGA patient cohorts, EXT2 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,343 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible EXT2-associated proteins across cancer lineages are CRTAP, EIF5A2, and FKBP9. Each is linked with EXT2 in more than 4 cancer types. Because this analysis shows association rather than direction, both EXT2-to-partner and partner-to-EXT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EXT2 versus CRTAP in OV, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EXT2→partner) and Y-score (partner→EXT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CRTAP →	+0.641	+0.534	<.001	.002	3	5
OV	EIF5A2 →	+0.885	+0.485	<.001	.003	3	5
BRCA	FKBP9 →	+0.639	+0.511	<.001	<.001	3	5
OV	PTK7 →	+0.495	+0.533	<.001	<.001	3	5
COAD	SERPINH1 →	+0.543	+0.413	<.001	<.001	3	5
OV	FLNA →	+0.559	+0.422	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,343 associations by consensus.

EXT2 vs CRTAP — OV

Explore this scatter interactively →