EXT1

Across TCGA patient cohorts, EXT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,488 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EXT1-associated proteins across cancer lineages are YWHAZ, CAMSAP2_S599, and CNN2. Each is linked with EXT1 in more than 3 cancer types. Because this analysis shows association rather than direction, both EXT1-to-partner and partner-to-EXT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EXT1 versus YWHAZ in LSCC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EXT1→partner) and Y-score (partner→EXT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	YWHAZ →	+0.372	+0.555	<.001	.001	3	4
LUAD	CAMSAP2_S599 →	+0.530	+0.542	<.001	.002	3	4
CCRCC	CNN2 →	+0.475	+0.352	<.001	.001	3	4
CCRCC	PLOD1 →	+0.464	+0.529	<.001	<.001	3	4
BRCA	PTPN14_S594 →	+0.540	+0.594	.001	<.001	3	4
BRCA	PVR →	+0.312	+0.358	.005	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,488 associations by consensus.

EXT1 vs YWHAZ — LSCC

Explore this scatter interactively →