EXT1

Across TCGA cell cohorts, EXT1 RNA expression is significantly associated with the RNA expression of many other genes, with 11,677 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible EXT1-associated genes across cancer lineages are ACTN1, CCN1, and AXL. Each is linked with EXT1 in more than 13 cancer types. Because this analysis shows association rather than direction, both EXT1-to-partner and partner-to-EXT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EXT1 versus ACTN1 in BLOOD_Lymphoma, with a Pearson correlation of 0.38.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EXT1→partner) and Y-score (partner→EXT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	ACTN1 →	+2.431	+1.282	.001	.003	3	14
STOMACH	CCN1 →	+4.597	+2.054	<.001	<.001	3	14
LUNG_NSCLC_LUSC	AXL →	+5.572	+1.528	<.001	<.001	3	13
LIVER	MYH9 →	+2.196	+1.755	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	TLN1 →	+1.376	+0.969	.006	.009	2	14
BONE	HEG1 →	+3.200	+1.560	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,677 associations by consensus.

EXT1 vs ACTN1 — BLOOD_Lymphoma

Explore this scatter interactively →