EXPH5

Across TCGA patient cohorts, EXPH5 protein abundance is significantly associated with the RNA expression of many other genes, with 6,528 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EXPH5-associated genes across cancer lineages are TMEM45B, TTC9, and PPL. Each is linked with EXPH5 in more than 4 cancer types. Because this analysis shows association rather than direction, both EXPH5-to-partner and partner-to-EXPH5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EXPH5 versus TMEM45B in BRCA, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EXPH5→partner) and Y-score (partner→EXPH5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TMEM45B →	+1.474	+0.385	.001	.002	3	5
UCEC	TTC9 →	+1.253	+0.497	<.001	<.001	3	4
UCEC	PPL →	+1.230	+0.503	<.001	<.001	3	4
UCEC	LMO7 →	+0.956	+0.506	.001	<.001	3	4
HNSC	MPZL2 →	+1.048	+0.601	.005	<.001	3	4
LSCC	NLRX1 →	+0.807	+0.436	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,528 associations by consensus.

EXPH5 vs TMEM45B — BRCA

Explore this scatter interactively →