EXPH5

Across TCGA cell cohorts, EXPH5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,108 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible EXPH5-associated GO terms across cancer lineages are Establishment of epithelial cell apical/basal polarity, Desmosome organization, and Keratinocyte development. Each is linked with EXPH5 in more than 11 cancer types. Because this analysis shows association rather than direction, both EXPH5-to-partner and partner-to-EXPH5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of epithelial cell apical/basal polarity grouped by EXPH5-low versus EXPH5-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EXPH5→partner) and Y-score (partner→EXPH5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Establishment of epithelial cell apical/basal polarity →	-0.246	-1.187	<.001	<.001	3	12
STOMACH	Desmosome organization →	+0.514	+1.955	.002	<.001	3	10
URINARY_TRACT	Keratinocyte development →	-0.563	-1.679	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Establishment of apical/basal cell polarity →	-0.250	-1.722	.001	<.001	3	10
URINARY_TRACT	Response to indole-3-methanol →	+0.231	+1.517	<.001	<.001	3	10
PANCREAS	Midbody abscission →	+0.087	+1.300	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,108 associations by consensus.

Establishment of epithelial cell apical/basal polarity by EXPH5 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →