EXOSC9

Across TCGA cell cohorts, EXOSC9 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,411 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EXOSC9-associated GO terms across cancer lineages are DNA-templated DNA replication, Double-strand break repair via break-induced replication, and Replication fork processing. Each is linked with EXOSC9 in more than 19 cancer types. Because this analysis shows association rather than direction, both EXOSC9-to-partner and partner-to-EXOSC9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated DNA replication grouped by EXOSC9-low versus EXOSC9-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EXOSC9→partner) and Y-score (partner→EXOSC9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA-templated DNA replication →	+0.125	+0.784	.003	.003	3	20
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair via break-induced replication →	+0.266	+1.069	<.001	.002	3	19
BONE	Replication fork processing →	+0.123	+0.903	<.001	<.001	3	19
BONE	DNA replication →	+0.110	+0.823	.003	.001	3	19
SOFT_TISSUE	Double-strand break repair →	+0.087	+0.795	<.001	.001	3	19
OESOPHAGUS	U1 snRNA 3'-end processing →	+0.136	+0.810	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,411 associations by consensus.

DNA-templated DNA replication by EXOSC9 expression — BONE

Explore this box plot interactively →