EXOSC10

Across TCGA cell cohorts, EXOSC10 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,256 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EXOSC10-associated GO terms across cancer lineages are DNA-templated DNA replication maintenance of fidelity, Regulation of telomerase RNA localization to Cajal body, and Replication fork processing. Each is linked with EXOSC10 in more than 19 cancer types. Because this analysis shows association rather than direction, both EXOSC10-to-partner and partner-to-EXOSC10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated DNA replication maintenance of fidelity grouped by EXOSC10-low versus EXOSC10-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EXOSC10→partner) and Y-score (partner→EXOSC10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA-templated DNA replication maintenance of fidelity →	+0.112	+0.860	.004	<.001	3	20
BONE	Regulation of telomerase RNA localization to Cajal body →	+0.118	+0.855	<.001	<.001	3	19
BONE	Replication fork processing →	+0.135	+1.014	.005	<.001	3	19
OESOPHAGUS	Mitotic chromosome condensation →	+0.222	+0.727	.001	<.001	3	19
OESOPHAGUS	Mitotic sister chromatid segregation →	+0.139	+0.541	<.001	<.001	3	18
BONE	Centrosome cycle →	+0.093	+0.914	.004	.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,256 associations by consensus.

DNA-templated DNA replication maintenance of fidelity by EXOSC10 expression — BONE

Explore this box plot interactively →