EXOG

Across TCGA cell cohorts, EXOG RNA expression is significantly associated with the go_rna of many other GO terms, with 4,996 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EXOG-associated GO terms across cancer lineages are Regulation of metaphase/anaphase transition of cell cycle, Regulation of mitotic metaphase/anaphase transition, and Regulation of sister chromatid segregation. Each is linked with EXOG in more than 17 cancer types. Because this analysis shows association rather than direction, both EXOG-to-partner and partner-to-EXOG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of metaphase/anaphase transition of cell cycle grouped by EXOG-low versus EXOG-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EXOG→partner) and Y-score (partner→EXOG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Regulation of metaphase/anaphase transition of cell cycle →	+0.132	+1.255	<.001	<.001	3	18
KIDNEY	Regulation of mitotic metaphase/anaphase transition →	+0.136	+1.255	<.001	<.001	3	18
KIDNEY	Regulation of sister chromatid segregation →	+0.125	+1.277	<.001	<.001	3	18
OVARY	Regulation of chromosome segregation →	+0.114	+1.056	<.001	<.001	3	18
OVARY	Microtubule nucleation →	+0.111	+1.014	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Microtubule organizing center organization →	+0.100	+1.199	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,996 associations by consensus.

Regulation of metaphase/anaphase transition of cell cycle by EXOG expression — KIDNEY

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