EXOC8

Across TCGA pan-cancer cohorts, EXOC8 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated EXOC8 data layer compared with 25 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher EXOC8 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated EXOC8 expression acts as an unfavorable survival marker.

KIRP and ACC are the cancer types where EXOC8 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Median	II,III,IV	0.148	0.771	<.001	24	view →
ACC	DFS	Median	All	0.195	0.748	.003	3	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

EXOC8–KIRP (OS)

Open the KIRP breakdown →