EXOC8

Across TCGA patient cohorts, EXOC8 protein abundance is significantly associated with the RNA expression of many other genes, with 11,782 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible EXOC8-associated genes across cancer lineages are DHRS7, ACOT1, and SLC39A9. Each is linked with EXOC8 in more than 5 cancer types. Because this analysis shows association rather than direction, both EXOC8-to-partner and partner-to-EXOC8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EXOC8 versus DHRS7 in HNSC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EXOC8→partner) and Y-score (partner→EXOC8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	DHRS7 →	+0.855	+0.190	.002	<.001	3	6
BRCA	ACOT1 →	+0.766	+0.170	<.001	<.001	3	5
BRCA	SLC39A9 →	+0.663	+0.201	<.001	<.001	3	5
BRCA	MPP5 →	+0.506	+0.182	.001	.002	3	5
LSCC	VTI1B →	+0.339	+0.103	<.001	.002	3	5
BRCA	CCNE1 →	-1.148	-0.210	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,782 associations by consensus.

EXOC8 vs DHRS7 — HNSC

Explore this scatter interactively →