EXOC8

Across TCGA cell cohorts, EXOC8 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. OESOPHAGUS shows the largest number of these associations.

The most reproducible EXOC8-associated genes across cancer lineages are CRYBB1, XAGE5, and OR2T8. Each is linked with EXOC8 in more than 1 cancer types. Because this analysis shows association rather than direction, both EXOC8-to-partner and partner-to-EXOC8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CRYBB1 grouped by EXOC8-low versus EXOC8-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EXOC8→partner) and Y-score (partner→EXOC8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	CRYBB1 →	+0.026	+4.906	<.001	.006	3	1
OESOPHAGUS	XAGE5 →	+0.066	+4.906	<.001	.006	3	1
OESOPHAGUS	OR2T8 →	+0.030	+4.906	<.001	.006	3	1
OESOPHAGUS	OR2M3 →	+0.006	+4.906	<.001	.006	3	1
OESOPHAGUS	OR10G2 →	+0.033	+4.906	<.001	.006	3	1
LARGE_INTESTINE	TBC1D21 →	+0.008	+3.700	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

CRYBB1 by EXOC8 expression — OESOPHAGUS

Explore this box plot interactively →