EXOC6

Across TCGA patient cohorts, EXOC6 protein abundance is significantly associated with the RNA expression of many other genes, with 12,117 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible EXOC6-associated genes across cancer lineages are PACSIN1, COPZ2, and PRRX1. Each is linked with EXOC6 in more than 4 cancer types. Because this analysis shows association rather than direction, both EXOC6-to-partner and partner-to-EXOC6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EXOC6 versus PACSIN1 in GBM, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EXOC6→partner) and Y-score (partner→EXOC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PACSIN1 →	+1.533	+0.259	<.001	<.001	3	5
OV	COPZ2 →	-0.767	-0.184	.008	.007	3	5
OV	PRRX1 →	-1.508	-0.287	<.001	<.001	3	4
BRCA	ARHGEF4 →	-1.072	-0.432	<.001	<.001	3	4
OV	CTHRC1 →	-1.164	-0.224	.005	.004	3	4
OV	SUGCT →	-1.290	-0.295	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,117 associations by consensus.

EXOC6 vs PACSIN1 — GBM

Explore this scatter interactively →