EXOC6

Across TCGA cell cohorts, EXOC6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,552 significant associations in total. BONE shows the largest number of these associations.

The most reproducible EXOC6-associated GO terms across cancer lineages are Vesicle tethering involved in exocytosis, Vesicle tethering, and External encapsulating structure organization. Each is linked with EXOC6 in more than 14 cancer types. Because this analysis shows association rather than direction, both EXOC6-to-partner and partner-to-EXOC6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle tethering involved in exocytosis grouped by EXOC6-low versus EXOC6-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EXOC6→partner) and Y-score (partner→EXOC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Vesicle tethering involved in exocytosis →	+0.095	+1.070	<.001	<.001	3	15
LUNG_SCLC	Vesicle tethering →	+0.073	+0.632	<.001	<.001	3	12
BONE	External encapsulating structure organization →	-0.176	-0.951	<.001	<.001	3	11
BONE	DNA replication initiation →	+0.200	+1.244	.003	.001	3	10
BONE	Regulation of DNA repair →	+0.054	+0.915	.001	<.001	3	10
BONE	G1/S transition of mitotic cell cycle →	+0.066	+1.155	.004	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,552 associations by consensus.

Vesicle tethering involved in exocytosis by EXOC6 expression — KIDNEY

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