EXOC4

Across TCGA patient cohorts, EXOC4 protein abundance is significantly associated with the RNA expression of many other genes, with 7,610 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible EXOC4-associated genes across cancer lineages are EXOC1, ATP6V1D, and IGKC. Each is linked with EXOC4 in more than 4 cancer types. Because this analysis shows association rather than direction, both EXOC4-to-partner and partner-to-EXOC4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EXOC4 versus EXOC1 in LSCC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EXOC4→partner) and Y-score (partner→EXOC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	EXOC1 →	+0.507	+0.113	.001	.001	3	5
HNSC	ATP6V1D →	+0.431	+0.079	.009	.009	3	4
BRCA	IGKC →	-2.164	-0.186	.002	.001	3	4
UCEC	IGHV1-18 →	-2.193	-0.193	.004	.001	3	4
LUAD	FAM30A →	-1.045	-0.149	<.001	<.001	3	4
UCEC	IGKV3-11 →	-2.222	-0.182	.004	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,610 associations by consensus.

EXOC4 vs EXOC1 — LSCC

Explore this scatter interactively →