Across TCGA patient cohorts, EXOC3L4 mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. COAD shows the largest number of these associations.

The most reproducible EXOC3L4-associated genes across cancer lineages are p62 Lck ligand, Tuberin, and AMPK_pT172. Each is linked with EXOC3L4 in more than 1 cancer types. Because this analysis shows association rather than direction, both EXOC3L4-to-partner and partner-to-EXOC3L4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EXOC3L4→partner) and Y-score (partner→EXOC3L4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p62 Lck ligand →	+0.617	+3.331	<.001	.005	3	1
UCEC	Tuberin →	+0.444	+2.817	.001	.036	3	1
UCEC	AMPK_pT172 →	+0.546	+2.183	.011	.035	2	1
COAD	Caspase-7-cleavedD198 →	+1.486	+2.815	<.001	.036	1	2
COAD	PCNA →	+0.269	+2.815	.048	.036	1	1
COAD	Cyclin-E1 →	+0.447	+2.815	.001	.036	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

EXOC3L4 survival (RNA) · tumor vs normal (RNA) · all EXOC3L4 data types