Across TCGA cell cohorts, EXOC3L4 mutation is significantly associated with the drug of many other genes, with 46 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EXOC3L4-associated genes across cancer lineages are Bosutinib, GSK1904529A, and Leflunomide. Each is linked with EXOC3L4 in more than 1 cancer types. Because this analysis shows association rather than direction, both EXOC3L4-to-partner and partner-to-EXOC3L4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EXOC3L4→partner) and Y-score (partner→EXOC3L4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Bosutinib →	+0.647	+2.700	<.001	.030	3	1
LARGE_INTESTINE	GSK1904529A →	+0.438	+2.678	.008	.037	3	1
LARGE_INTESTINE	Leflunomide →	+0.323	+2.769	.010	.040	3	1
LARGE_INTESTINE	PAK_5339 →	+0.322	+2.678	.031	.037	3	1
LARGE_INTESTINE	150412 →	+0.484	+2.777	.003	.038	3	1
LARGE_INTESTINE	Schweinfurthin A →	+0.595	+2.649	.023	.046	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

Exploration

EXOC3L4 survival (RNA) · tumor vs normal (RNA) · all EXOC3L4 data types