EXOC3L2

Across TCGA patient cohorts, EXOC3L2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,135 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible EXOC3L2-associated genes across cancer lineages are FLT1, ROBO4, and CLEC14A. Each is linked with EXOC3L2 in more than 4 cancer types. Because this analysis shows association rather than direction, both EXOC3L2-to-partner and partner-to-EXOC3L2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EXOC3L2 versus FLT1 in OV, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EXOC3L2→partner) and Y-score (partner→EXOC3L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FLT1 →	+1.020	+0.496	<.001	.001	3	5
OV	ROBO4 →	+0.820	+0.611	<.001	<.001	3	5
UCEC	CLEC14A →	+0.632	+0.301	.001	.001	3	5
OV	CDH5 →	+1.037	+0.477	<.001	<.001	3	5
UCEC	PCDH17 →	+0.547	+0.330	<.001	<.001	3	4
OV	KDR →	+1.120	+0.587	<.001	.001	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,135 associations by consensus.

EXOC3L2 vs FLT1 — OV

Explore this scatter interactively →