EXOC3L2

Across TCGA cell cohorts, EXOC3L2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,606 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EXOC3L2-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Negative regulation of myoblast fusion, and Regulation of base-excision repair. Each is linked with EXOC3L2 in more than 5 cancer types. Because this analysis shows association rather than direction, both EXOC3L2-to-partner and partner-to-EXOC3L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by EXOC3L2-low versus EXOC3L2-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EXOC3L2→partner) and Y-score (partner→EXOC3L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Negative regulation of syncytium formation by plasma membrane fusion →	+0.049	+0.981	.006	.005	3	6
BLOOD_Leukemia	Negative regulation of myoblast fusion →	+0.052	+0.973	.004	.005	3	5
LARGE_INTESTINE	Regulation of base-excision repair →	+0.059	+0.024	<.001	.006	3	4
LUNG_NSCLC_LUSC	Establishment of protein localization to organelle →	+0.039	+0.021	.005	.009	2	5
BLOOD_Leukemia	Regulation of cell fate commitment →	+0.109	+1.252	<.001	<.001	3	4
BLOOD_Leukemia	Schwann cell differentiation →	+0.054	+0.800	.003	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,606 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by EXOC3L2 expression — BLOOD_Leukemia

Explore this box plot interactively →