EXOC3L1

Across TCGA cell cohorts, EXOC3L1 mutation is significantly associated with the RNA expression of many other genes, with 243 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EXOC3L1-associated genes across cancer lineages are SLC17A2, NCR2, and TIFA. Each is linked with EXOC3L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both EXOC3L1-to-partner and partner-to-EXOC3L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC17A2 grouped by EXOC3L1-low versus EXOC3L1-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EXOC3L1→partner) and Y-score (partner→EXOC3L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	SLC17A2 →	+0.173	+4.217	.001	.005	3	2
SOFT_TISSUE	NCR2 →	+0.042	+5.369	<.001	.004	3	2
LARGE_INTESTINE	TIFA →	+0.885	+3.212	.002	.006	3	2
BLOOD_Leukemia	DSCAML1 →	+1.159	+4.212	<.001	<.001	3	2
URINARY_TRACT	LECT2 →	+0.874	+4.217	<.001	.005	3	1
URINARY_TRACT	DRD3 →	+0.017	+4.087	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 243 associations by consensus.

SLC17A2 by EXOC3L1 expression — URINARY_TRACT

Explore this box plot interactively →