EXOC3

Across TCGA patient cohorts, EXOC3 protein abundance is significantly associated with the RNA expression of many other genes, with 9,751 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible EXOC3-associated genes across cancer lineages are ARRDC4, SMCHD1, and PSAT1. Each is linked with EXOC3 in more than 3 cancer types. Because this analysis shows association rather than direction, both EXOC3-to-partner and partner-to-EXOC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EXOC3 versus ARRDC4 in OV, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EXOC3→partner) and Y-score (partner→EXOC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ARRDC4 →	+0.754	+0.155	<.001	<.001	3	4
HNSC	SMCHD1 →	-0.500	-0.137	<.001	<.001	3	4
BRCA	PSAT1 →	-2.519	-0.209	<.001	<.001	3	4
GBM	SKA1 →	-0.728	-0.146	.004	.001	3	4
UCEC	CCNB2 →	-0.888	-0.159	<.001	<.001	3	4
GBM	ARHGAP11A →	-0.778	-0.117	<.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,751 associations by consensus.

EXOC3 vs ARRDC4 — OV

Explore this scatter interactively →