EXOC3

Across TCGA cell cohorts, EXOC3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,083 significant associations in total. CNS shows the largest number of these associations.

The most reproducible EXOC3-associated GO terms across cancer lineages are Vacuolar transport, Regulation of protein localization to endoplasmic reticulum, and Endosomal transport. Each is linked with EXOC3 in more than 16 cancer types. Because this analysis shows association rather than direction, both EXOC3-to-partner and partner-to-EXOC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vacuolar transport grouped by EXOC3-low versus EXOC3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EXOC3→partner) and Y-score (partner→EXOC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Vacuolar transport →	+0.052	+0.839	.001	.007	3	17
OESOPHAGUS	Regulation of protein localization to endoplasmic reticulum →	+0.158	+1.079	.002	.005	3	16
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.068	+1.029	<.001	<.001	3	15
BREAST	Regulation of Golgi inheritance →	+0.166	+1.188	<.001	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Retrograde transport, endosome to Golgi →	+0.082	+1.032	<.001	<.001	3	14
STOMACH	Positive regulation of intracellular protein transport →	+0.085	+0.806	<.001	.006	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,083 associations by consensus.

Vacuolar transport by EXOC3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →