EXOC2

Across TCGA patient cohorts, EXOC2 mutation is significantly associated with the total protein of many other genes, with 39 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EXOC2-associated genes across cancer lineages are TFRC, ERK2, and PCNA. Each is linked with EXOC2 in more than 2 cancer types. Because this analysis shows association rather than direction, both EXOC2-to-partner and partner-to-EXOC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFRC grouped by EXOC2-low versus EXOC2-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EXOC2→partner) and Y-score (partner→EXOC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	TFRC →	+0.519	+3.169	.033	.019	3	2
UCEC	ERK2 →	+0.155	+1.584	.013	.017	3	2
UCEC	PCNA →	+0.238	+2.321	<.001	<.001	3	2
UCEC	c-Kit →	-0.161	-1.459	.033	.012	3	2
STAD	Caspase-7-cleavedD198 →	+0.881	+3.000	.021	.036	1	3
UCEC	14-3-3_beta →	-0.070	-2.088	.030	.016	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

TFRC by EXOC2 expression — BLCA

Explore this box plot interactively →