EXOC2

Across TCGA cell cohorts, EXOC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,090 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EXOC2-associated GO terms across cancer lineages are Negative regulation of RNA export from nucleus, Mitotic cytokinesis, and Cytoskeleton-dependent cytokinesis. Each is linked with EXOC2 in more than 13 cancer types. Because this analysis shows association rather than direction, both EXOC2-to-partner and partner-to-EXOC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of RNA export from nucleus grouped by EXOC2-low versus EXOC2-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EXOC2→partner) and Y-score (partner→EXOC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of RNA export from nucleus →	+0.146	+1.185	.004	.003	3	14
BREAST	Mitotic cytokinesis →	+0.087	+0.906	<.001	<.001	3	13
BREAST	Cytoskeleton-dependent cytokinesis →	+0.093	+0.835	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Vesicle tethering involved in exocytosis →	+0.093	+0.563	.002	.008	2	14
BREAST	Cytokinesis →	+0.095	+0.877	<.001	<.001	3	13
STOMACH	Vesicle-mediated transport to the plasma membrane →	+0.058	+0.585	.005	.008	2	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,090 associations by consensus.

Negative regulation of RNA export from nucleus by EXOC2 expression — STOMACH

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