EXOC1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, EXOC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,066 significant associations in total. BONE shows the largest number of these associations.

The most reproducible EXOC1-associated GO terms across cancer lineages are Golgi vesicle transport, Membrane fission, and Vesicle budding from membrane. Each is linked with EXOC1 in more than 15 cancer types. Because this analysis shows association rather than direction, both EXOC1-to-partner and partner-to-EXOC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi vesicle transport grouped by EXOC1-low versus EXOC1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EXOC1→partner) and Y-score (partner→EXOC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UPPER_AERODIGESTIVE_TRACTGolgi vesicle transport →+0.089+1.090<.001<.001315
LIVERMembrane fission →+0.075+0.728.004.001216
SKINVesicle budding from membrane →+0.063+0.566<.001<.001314
UPPER_AERODIGESTIVE_TRACTPositive regulation of protein binding →+0.126+1.001<.001<.001314
UPPER_AERODIGESTIVE_TRACTCilium movement involved in cell motility →-0.146-0.960<.001<.001313
BREASTGolgi organization →+0.065+0.700<.001<.001313
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,066 associations by consensus.

Golgi vesicle transport by EXOC1 expression — UPPER_AERODIGESTIVE_TRACT

Box plot of Golgi vesicle transport in EXOC1-low vs EXOC1-high samples in UPPER_AERODIGESTIVE_TRACT.

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Exploration