EXO5

Across TCGA patient cohorts, EXO5 protein abundance is significantly associated with the RNA expression of many other genes, with 88 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible EXO5-associated genes across cancer lineages are TRMU, KHNYN, and GALNT7. Each is linked with EXO5 in more than 1 cancer types. Because this analysis shows association rather than direction, both EXO5-to-partner and partner-to-EXO5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EXO5 versus TRMU in BRCA, with a Pearson correlation of 0.83.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EXO5→partner) and Y-score (partner→EXO5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TRMU →	+0.895	+1.039	.001	.007	3	1
BRCA	KHNYN →	-1.314	-0.787	.002	.002	3	1
BRCA	GALNT7 →	-3.342	-0.820	.001	.004	3	1
BRCA	ARFGEF3 →	-2.745	-0.952	<.001	.003	3	1
BRCA	RALGPS2 →	-1.942	-0.790	.007	.002	3	1
BRCA	MEF2D →	-0.803	-0.722	.006	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 88 associations by consensus.

EXO5 vs TRMU — BRCA

Explore this scatter interactively →